A Simple Guide to Corneal Ulcer

A Simple Guide to Corneal Ulcer
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What is Corneal ulcer?
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Corneal ulcer is a inflammatory disease of the surface of the cornea which causes local destruction of the superficial layer of the cornea resulting in ulcers.

Corneal ulcers can be infectious(due to infection) or non infectious(due to injury or autoimmune disease)


Who is affected by corneal ulcer?
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Corneal ulcers may be present more frequently in patients with :
Vitamin A deficiency

autoimmune disease

neurological disorders like facial palsy

What is the Cause of corneal ulcer?
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The causes of Corneal ulcers can divided into 2 type:
Infections:
1. Bacterial infection such as Streptococci, Staphhylococci, pneumococci, pseudomonas

2. Viral infections such as herpes simplex, herpes zoster,

3. Fungal infection

Non-infection:
1.Injury due to hard contact lens, abrasions from trauma, accidental scratch

2.autoimmune disease

3.Systemic disease

What are the Symptoms and signs of corneal ulcer?
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Symptoms varies from mild to severe:

1.Severe pain in the eye or around the eye and eyebrow especially with infectious causes. Non-infectious causes may not give rise to pain.

2.Red eye - increased blood flow through inflamed eye shows up the blood vessels

3.Tearing -excess tears from inflammation

4.Discharge -may be pus discharge from eyes especially in the morning

5.Light sensitivity - sensitive to bright lights

Signs:

1.White spot on the cornea, that depending on the severity of the ulcer, may not be visible with the naked eye

2.increased dilated blood vessels present due to inflammation


How do you make the Diagnosis of corneal ulcer?
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The presence of a corneal ulcer can be seen using a slit lamp microscope.
Sometimes a dye fluorescein may be dropped into the eye making it more visible and easier to detect.

What investigation are necessary in Corneal ulcer?
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If the patient is suspected to have infection(pus discharge from the eyes), a tissue culture of the corneal cells(gently scraped from the ulcer) may be necessary to determine the type of micro-organism infecting the eye.


What are the complications of corneal ulcer?
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The complication is always the risk of :

1.Severe infection of the eye especially with pseudomonas infection causing infection of the anterior chamber of the eye and then spreading to the rest of eye resulting in loss of an eye.

2.Scarring of the corneal ulcer resulting in partial loss of vision

What is the treatment of corneal ulcer?
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Treatment depends on the type of corneal ulcer:

Infection:
1.Bacterial infection requires more intense treatment with oral antibiotics and antibiotic eye drops (given every 15 minutes)

2.Viral infections are usually treated with acyclovir tablets orally and acyclovir eye cream

3.Fungal infections are less common but are usually treated with antifungal medicine and eye drops.

In all infection cases, corticosteroid medications are not given.
Painkillers such as paracetamol can be given for pain

Non-infection:
1.Corticosteroid eye drops are usually given to reduce the inflammation

2.Antibiotic are also given to prevent infections of the ulcer.

In all cases the eye should be covered with eye pad until the epithelium of the ulcer heals about 10-14 days.

What is the prognosis of corneal ulcer?
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The prognosis depends on the severity of the disease

Most cases can be healed if detected early.

There may be minimum scarring of the cornea with possible loss of some vision.

Rarely the eye may be lost if there is severe infection and no treatment.


What are preventive measures in corneal ulcer?
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1. A nutritious diet with vitamin supplements can strengthen the body resistance against illness.

2.Avoid the use of infected contact lens lotion

3.A soft lens are more prone to eye infection. Always wash the hands before using any contact lens.

4.Avoid rubbing the eyes with dirty hands or tissues

5.A healthy lifestyle with less stress and mild exercise is always good for the body.