DOC I AM AGING
Aging is the process where the human body accumulate damage to its cells. tissues and organs as it grows older.
This accumulated damage is believed to be the result of oxidation damage to the cell contents from free radicals.
Average and maximum lifespans:
The maximum life span for humans is currently maximized at approximately 120 years
Average lifespan in a population is lowered:
1.infant and child mortality is frequently linked to infectious diseases or nutrition problems.
2.accidents and age-related chronic disease such as cancer or cardiovascular disease play an increasing role in mortality.
Extension of lifespan can often be achieved by:
1.improved medical care,
2.vaccinations,
3.good diet,
4.exercise
5.avoidance of bad habits such as smoking.
Maximum lifespan is determined by
1.the rate of aging inherent in its genes and by environmental factors.
2.calorie restriction.
3.breeding from only older members.
Anti-aging medicine is the study of slowing down or reversing the processes of aging to extend both the maximum and average lifespan.
In Theory extension of maximum lifespan could be achieved by
1. reducing the rate of aging damage,
2. periodic replacement of damaged tissues,
3. molecular repair or rejuvenation of deteriorated cells and tissues
4. enhancement of telomerase enzyme activity.
Diets and supplements
1.nutrition—diets or supplements—as a means to extend lifespan
2.antioxidant supplements, such as Vitamin C, Vitamin E, Q10, lipoic acid, carnosine, and N-acetylcysteine, may extend life if the free radical theory of extending life is to be believed
3.oxytocin, insulin, human chorionic gonadotropin (hCG), and erythropoietin (EPO).
4.Resveratrol is a sirtuin stimulant that appears to extend lifespan in simple organisms
Hormone treatments
1.low-dose GH treatment for adults with GH deficiency changes the body composition by
a.increasing muscle mass, decreasing fat mass,
b.increasing bone density and muscle strength,
c.improves cardiovascular parameters (i.e. decrease of LDL cholesterol)
d.affects the quality of life without significant side effects.
Nanotechnology
nanomedicine could give rise to life extension through the repair of many processes thought to be responsible for aging.
Cloning and body part replacement
therapeutic cloning and stem cell research could one day provide a way to generate cells, body parts, or even entire bodies that would be genetically identical to a prospective patient.
Cryonics
1.storing the body at low temperatures after death may provide an entry into a future in which advanced medical technologies may allow resuscitation and repair.
2.cryogenic temperatures will minimize changes in biological tissue for many years, giving the medical community ample time to cure all disease, rejuvenate the aged and repair any damage that is caused by the cryopreservation process.
Strategies for Engineered Negligible Senescence (SENS)
combine existing and predicted future biochemical and genetic techniques to a cure for cancer, stem cell treatments, addition of new enzymes to the human body and moving mitochondrial DNA to the cellular nucleus.
Genetic modification
artificial genes are integrated with an organism to replace mutated or otherwise deficient genes,
Targeting catalase to the mitochondria resulted in a 20% lifespan increase in mice, and improved performance in therapeutically infected mice.
Fooling genes
an approach to life-extension that involves fooling genes into thinking the body is young
The basic idea is that our bodies are composed of genes that activate throughout our lifetimes, some when we are young, and others when we are older.
These genes are activated by environmental factors and the changes caused by these genes activating can be fatal.
Aging is the process where the human body accumulate damage to its cells. tissues and organs as it grows older.
This accumulated damage is believed to be the result of oxidation damage to the cell contents from free radicals.
Average and maximum lifespans:
The maximum life span for humans is currently maximized at approximately 120 years
Average lifespan in a population is lowered:
1.infant and child mortality is frequently linked to infectious diseases or nutrition problems.
2.accidents and age-related chronic disease such as cancer or cardiovascular disease play an increasing role in mortality.
Extension of lifespan can often be achieved by:
1.improved medical care,
2.vaccinations,
3.good diet,
4.exercise
5.avoidance of bad habits such as smoking.
Maximum lifespan is determined by
1.the rate of aging inherent in its genes and by environmental factors.
2.calorie restriction.
3.breeding from only older members.
Anti-aging medicine is the study of slowing down or reversing the processes of aging to extend both the maximum and average lifespan.
In Theory extension of maximum lifespan could be achieved by
1. reducing the rate of aging damage,
2. periodic replacement of damaged tissues,
3. molecular repair or rejuvenation of deteriorated cells and tissues
4. enhancement of telomerase enzyme activity.
Diets and supplements
1.nutrition—diets or supplements—as a means to extend lifespan
2.antioxidant supplements, such as Vitamin C, Vitamin E, Q10, lipoic acid, carnosine, and N-acetylcysteine, may extend life if the free radical theory of extending life is to be believed
3.oxytocin, insulin, human chorionic gonadotropin (hCG), and erythropoietin (EPO).
4.Resveratrol is a sirtuin stimulant that appears to extend lifespan in simple organisms
Hormone treatments
1.low-dose GH treatment for adults with GH deficiency changes the body composition by
a.increasing muscle mass, decreasing fat mass,
b.increasing bone density and muscle strength,
c.improves cardiovascular parameters (i.e. decrease of LDL cholesterol)
d.affects the quality of life without significant side effects.
Nanotechnology
nanomedicine could give rise to life extension through the repair of many processes thought to be responsible for aging.
Cloning and body part replacement
therapeutic cloning and stem cell research could one day provide a way to generate cells, body parts, or even entire bodies that would be genetically identical to a prospective patient.
Cryonics
1.storing the body at low temperatures after death may provide an entry into a future in which advanced medical technologies may allow resuscitation and repair.
2.cryogenic temperatures will minimize changes in biological tissue for many years, giving the medical community ample time to cure all disease, rejuvenate the aged and repair any damage that is caused by the cryopreservation process.
Strategies for Engineered Negligible Senescence (SENS)
combine existing and predicted future biochemical and genetic techniques to a cure for cancer, stem cell treatments, addition of new enzymes to the human body and moving mitochondrial DNA to the cellular nucleus.
Genetic modification
artificial genes are integrated with an organism to replace mutated or otherwise deficient genes,
Targeting catalase to the mitochondria resulted in a 20% lifespan increase in mice, and improved performance in therapeutically infected mice.
Fooling genes
an approach to life-extension that involves fooling genes into thinking the body is young
The basic idea is that our bodies are composed of genes that activate throughout our lifetimes, some when we are young, and others when we are older.
These genes are activated by environmental factors and the changes caused by these genes activating can be fatal.
