A Family Doctor's Tale -HYPERKALEMIA

DOC I HAVE HYPERKALEMIA

Hyperkalemia is defined as high Potassium in the blood.

Normal blood potassium varies from 3.4 to 5.7 mmol per liter.
Extracellular potassium level represents only 2 per cent of the total body potassium.

Potassium is a major determinent of intracellular volume of cells and intracellur osmolarity.
It is a also an important cofactor in many metabolic processes.
The resting membrane potential and excitable tissues like nerves is mainly determined by ratio of intracellular to extracellular potassium concentrations.

Plasma and extracellular potassium levels are influenced by many factors particularly acid based balance. Acidosis moves potassium out of cells while alkalosis shifts potassium into cells.

Hyperkalemia occurs with impaired renal function

Symptoms of Hyperkalemia:
1.cardiac arrhythmias

2.muscle weakness especially peripheral muscles

Diagnosis:
1.Plasma potassium levels

2.Electrocardogram shows peaked T waves, prolonged PR intervals,
complete heart block and atrial asystole

Treatment:
1.glucose with insulin infusion  can drives potassium into cells lowering the plasma potassium( U insulin for every 2gms of glucose)

2.Infusion of sodium bicarbonate to induce alkalosis

3.Infusion of calcium bicarbonate to induce alkalosis

4.administer potassium binding resins by mouth

5.hemodialysis

Prognosis:
is good in most cases depending on rapidity of treatment and cause.