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Monday, June 6, 2011

A Family Doctor's Tale - DYSENTERY

DOC I HAVE DYSENTERY

Dysentery is an acute invasive infection  of the lining of the intestines caused by a micro-organism such as bacteria or paraste resulting in leakage of fluid from the cell into the intestine(diarrhea) sometimes with bloody mucus, abdominal pain or vomiting.

The causes of Dysentery are:
Bacteria:
1.Shigella

2.E.Coli

Parasitic:

amebic

Transnission occurs most often by close personal contact through hands or soiled clothing or fecal-oral contamination.

Stools can contain red blood cells and white blood cells.

There may blood in the stools.

The symptoms of Dysentery are:
1. watery diarrhea with blood and mucus

2. cramping abdominal pain

3. fever

4. headache and bodyaches

5. serious fluid loss especially in children

6. loss of appetite and energy

Dysentery is transmitted through:
Dysentery can be highly contagious.

The germs are commonly transmitted by people with unwashed hands.

People can get the germs through close contact with infected individuals by sharing their food, drink, or eating utensils, or by eating food or drinking beverages that are contaminated with the germs.

The diagnosis of Dysentery is made by:
1.Doctors generally diagnose Dysentery based on the symptoms and a physical examination.

2.stool sample to test for microscopic examination and stool culture

Microscopic examination shows the presence of red blood cells and polymorphs white blood cells.

Treatment of  Dysentery is by:
1.Because of the excessive fluid loss, correction of fluid and electrolyte balance is the most important part of treatment.

Prompt treatment may be needed to prevent dehydration which is the loss of fluids from the body. Important salts or minerals, known as electrolytes, can also be lost with the fluids. Dehydration can be caused by diarrhea, excessive urination, excessive sweating, or by not drinking enough fluids because of nausea, difficulty swallowing, or loss of appetite.

The symptoms of dehydration are
excessive thirst
dry mouth
little or no urine or dark yellow urine
sunken eyes
severe weakness or lethargy
dizziness or lightheadedness

Mild dehydration can be treated by drinking liquids.

Severe dehydration may require intravenous fluids and hospitalization.

Untreated severe dehydration can be life threatening especially in babies, young children and the elderly.

2.Antibiotics is necessary,the choice of which depends on the sensitivity of bacteria to the antibiotic.

Anti parasitic drug for amebic dysentery is usually metronidazole

3.Relief of symptoms include an antispasmodic drug to stop abdominal cramps, medicine to harden the stools such as kaolin and slow down the intestinal movement (lomotil or loperamide).

The following steps may help relieve the symptoms of Dysentery.
1.Allow your gastrointestinal tract to settle by not eating for a few hours.

2.Sip small amounts of clear liquids or suck on ice chips if vomiting is still a problem.

3.Give infants and children oral rehydration solutions to replace fluids and lost electrolytes.

4.Gradually reintroduce food, starting with bland, easy-to-digest food, like porridge or soups.

5.Avoid dairy products, caffeine, and alcohol until recovery is complete.

6.Get plenty of rest.

Prognosis:
Symptoms usually improve within one to 2 days after the onset of treatment.

Outcome is usually excellent with appropriate treatment.

Prevention of dysentery is by:
1.washing of  hands thoroughly for 20 seconds after using the bathroom or changing diapers

2.washing of  hands thoroughly for 20 seconds before eating

3.disinfecting contaminated surfaces such as counter tops and baby changing stations

4.Avoid eating or drinking foods or liquids that might be contaminated

5.Avoid raw vegetables or meat

Saturday, June 4, 2011

A Family Doctor's Tale -CONTACT DERMATITIS

DOC I HAVE CONTACT DERMATITIS


Contact Dermatitis is a common skin condition which presents as a erythematous or vesicular rash on face, neck, hands and other areas in contact with external environmental substances.

The cause of Contact Dermatitis is related to the exposure of the skin to the external environmental substances, chemicals or plants.

There may be a latent interval of days or years between first exposure and development of sensitization.

Virtually any substance can cause sensitivity of the epidermis of the skin.

Some possible triggers are:
1.Metals especially nickel from bracelet, pendants, neck chains, or chrome from watches, etc

2.Dyes from comestics,lipstick, clothes, hair dyes

3.Chemicals from perfumes, soaps, shaving cream, antiseptic creams

4.drugs such as penicillin, sulphonamides, tetracycline, neomycin, aspirin, NSAIDs, ointment bases,

5.Plants such as poison ivy, flowers, pollens, primrose just to name a few can cause skin allergy

6.Animals - the fur from animals can cause contact dermatitis

Contact Dermatitis affects both sexes equally.

Symptoms and signs of Contact Dermatitis are:
Typical features of Contact Dermatitis are:

1.vesicular or bubbles in areas most exposed to the external environmental substance

2.erythrematous or red rashes in areas most exposed to direct contact

3.hives or urticaria from direct contact such as pollens

4.weeping eczema in severe cases

Diagnosis:

skin patch tests

Treatment of an Contact Dermatitis treatment routine is:

1. Avoid exposure to causative substance

2.application of nonprescription corticosteroid creams and ointments to reduce inflammation
if the condition persists, worsens, or does not improve satisfactorily.

Hydrocotisone cream and ointment are preferred to prevent side effects such as skin thinning.

3.For severe flare-ups, your doctor may prescribe oral corticosteroids (this treatment is not recommended for long-term use).

4.sedative antihistamines are sometimes used to reduce the itch

Prognosis of Contact Dermatitis:

good to excellent in most cases with avoidance of contact substance

Recurrence is always possible due to recontact or new substance allergy

Prevention of Contact Dermatitis is by:
Contact Dermatitis can usually be avoided with some simple precautions.

1.Avoid contact with the causative environmental substance which has been identified

2.Avoid contact with drugs or cosmetics which can trigger off Contact dermatitis

3.Avoid contact with foods having dyes and preservatives

Thursday, June 2, 2011

A Family Doctor's Tale - PHOTO DERMATITIS

DOC I HAVE PHOTO DERMATITIS

Photo Dermatitis is a common skin condition which presents as a erythematous or vesicular rash on face, neck, hands and other areas exposed to sunlight.

The cause of Photo Dermatitis is related to the exposure of the skin to the sun.
However some possible triggers are:
1.Genetic

Genes play a part in Photo Dermatitis as the condition runs in families

2.External causes

Photo sensitivity:certain exogenous sensitizers play a part in the development of Photo Dermatitis.

a.drugs such as phenothiazines, thiazides and tetracycline

b.cosmetic such as lipstick, perfumes, soaps, shaving cream, antiseptic creams, even sun screening agents (especially if they contain coal tar)

c.irritating chemicals which exaggerated the photosensitzing effect of the sun

d.sunburn reaciion which aggarvated the skin to react as rashes.

e.Photo allergic rash which persist for years

f. injury by ultraviolet light

g.feeling too hot and/or sweating will cause an outbreak.

h.Stress can also sometimes aggravate an existing flare-up.

Photo Dermatitis affects both sexes equally.

The symptoms and signs of Photo Dermatitis are:
Typical features of Photo Dermatitis are:

1.vesicular or bubbles in areas most exposed to light

2.erythrematous or red rashes in areas most exposed to light

3.some occurs following severe sunburn

4.some are seasonal with recurrance in early spring and summer

5.actinoid reticuloid skin rash affecting the face and hands are also seen in chronic photo dermatitis patients

Photo Dermatitis is  diagnosed by:
1.History and appearance of the rash

2.Photo patch testing

3.Determination of light wavelength causing photo dermatitis

Treatment of an Photo Dermatitis treatment routine is:
1. Avoid ultraviolet light especially long wave ultraviolet light

2. application of lotions or creams to protect the skin against the sun

3.chloroquine sulphate 200mg daily may be useful for some patients over short periods

4.application of nonprescription corticosteroid creams and ointments to reduce inflammation
if the condition persists, worsens, or does not improve satisfactorily.

Hydrocotisone cream and ointment are preferred to prevent side effects such as skin thinning.

5.For severe flare-ups, your doctor may prescribe oral corticosteroids (this treatment is not recommended for long-term use).

6.sedative antihistamines are sometimes used to reduce the itch

Prognosis:

1.good to excellent in most cases with phot toxic eruptions

2.good to fair with photo allergic reactions

3.Some patients reacts persistently to light without exposure to an antigen.

Prevention of  Photo Dermatitis is by:
Photo Dermatitis outbreaks can usually be avoided with some simple precautions.

The following suggestions may help to reduce the severity and frequency of flare-ups when exposed to the sun:

1.use sun screen

2.Avoid drugs or cosmetics which can trigger off photo dermatitis

3.Avoid sweating or overheating

4.Reduce stress

5.Avoid harsh soaps, detergents, and solvents

6.Avoid environmental factors that trigger allergies (e.g., pollens, molds, mites, and animal dander)

7.Be aware of any foods that may cause an outbreak and avoid those foods

Tuesday, May 31, 2011

A Family Doctor's Tale - ENCEPHALITIS

DOC I HAVE ENCEPHALITIS

Encephalitis is a serious medical disease which causes inflammation and infection of the brain.

The causes of Encephalitis may be divided into:

Infections:
1.viral infections are the most common
(herpes simplex virus, mumps, measles, rubella, chickenpox, West Nile Encephalitis, Japanese Encephalitis, St Lious Encephalitis).

Of these viruses, herpes simplex virus is the most serious and can cause fatality.

2.bacterial infections such as meningoccocus (Neisseria meningitidis) and pneumococcus(Streptococcus pneumoniae) can be serious and fatal in some cases.

Meningococcal Encephalitis can cause outbreaks(spread easily).

3.fungi,
Cryptococcus neoformans is the most common cause of fungal Encephalitis

4.Parasitic
Examples are Toxoplasmosis, malaria, amoeba, Lyme Disease

The symptoms which often defines Encephalitis are:

1.Severe headache

2.Fever

3.Irritabilty

4.Confusion

5.Drowsiness and fatigue

Other symptoms are:

6.seizures and convulsions

7.vomiting

8.hallucinations

9.memory problems

10.tremors

11.weakness of the hands and legs

12.incontinence of urinary and bowel movement

The diagnosis of Encephalitis is made by:
1.Typical symptoms of fever, headache, confusion .

2.Physical examination shows confusion ,drowsiness and signs of neck rigidity

3.blood tests (complete blood count, ESR and blood culture)

4.cerebrospinal fluid analysis (CSF) via lumbar puncture is examined for increased white blood cells and protein content,  normal glucose level. Red blood cells may be present if there is bleeding. Sometimes the CSF may show the presence of micro-organisms.

This test should not be done if there is suspected cerebral mass lesion or raised intracranial pressure (head injury, localizing neurological signs, or signs of raised ICP).

5.CT or MRI of the brain and spine with MRI preferred over CT because it can detect more easily areas of cerebral edema,tumors, ischemia, and meningeal inflammation.

The complications of Encephalitis are:
1.Neurological deficits

2.deafness

3.learning disorders in children

4.brain infarction,

5.septic shock,

6.adult respiratory distress syndrome

7.seizures also more in children

8.pneumonia especially in the elderly

The treatment of Encephalitis is:
1.Hospitalisation should be immediate as Encephalitis can be a life threatening condition.

2.Antibiotics such as cephalosporin, ampicillin, chloramphenicol, intravenous vancomycin to be started even before doing lumbar puncture.

Acyclovir may be given for herpes virus infection

High dosages of antifungals may be given for Fungal Encephalitis for a prolonged period of time

3.corticosteroids is useful to reduce swelling and inflammation in the brain

4.Sedatives may be needed for irritabilty and restlessness

5.High-flow oxygen

6.intravenous fluids

The prognosis of Encephalitis is:
This depends on the severity and type of infection.

Viral infections except for herpes simplex usually recover quickly.

Bacterial infections such as meningococcus and pneumonia are more dangerous.

The Preventive measures taken for Encephalitis are:
Vaccinations against Haemophilus influenzae in children and adults has reduced the incidence of this form of meningitis and encephalitis.

Mumps vaccination as part of Measles,mumps and rubella vaccine(MMR) has reduced the incidence of mumps related form of meningitis and encephalitis

Vaccinations against Japanese Encephalitis is given for travelers going to endemic places with Japanese Encephalitis.

Sunday, May 29, 2011

A Family Doctor's Tale - CANCER OF VULVA

DOC I HAVE CANCER OF THE VULVA

Cancer of the vulva is  a rare cancer in women which affects the vulva occurring usually in older women past menopause.

The average age is over 60.

The cancer is usually a squamous carcinoma.

Rare tumors are melanoma, basal cell carcinoma and sarcoma.

The most common site is the labium majus(side wall of the vulva) , followed by the clithoris but it may arise anywhere including the urethral area.

The cancer can spread locally to involve the whole vulva and invade the vagina.

Secondary spread of the cancer is along the lymphatic system.

The symptoms and signs of  cancer of the vulva are:

1.The cancer is usually symptomless until it ulcerates.

2.It can presents as a lump which is cauliflower in appearance or ulcerated or indurated.

3.inguinal lymph nodes may be enlarged in cases of spread.

4.There may be pain with ulceration or long standing itch.

Diagnosis of cancer of the vulva is by:

1.Physical examination may revealed a lump or more in the vulva region.

2.Biopsy of the lump may reveal cancer

3.Ultrasound may be able to detect any spread to the vagina, uterus or lymph gland.

The treatment of Cancer of the vulva is  :

1.Surgery:
If there is no evidence of spread, usually removal of the cancerous lump is sufficient.

If the evidence of spread to the entire vulva region, radical vulvectomy may be done together with removal of the inguinal lymph nodes.

Chemotherapy:
Chemotherapy may help to prevent the spread of the cancer or to prevent a reccurance.

Radiotherapy :
Radiotherapy is not a treatment of choice


Squamous cell carcinoma is relatively resistant to radiotherapy.


The vulval skin is also very sensitive the burning effect of radiotheray.


However in the very old and frail patients, radiotherapy may be considered as an alternative to multilating operation.

Prognosis of cancer of the vulva is:
If the lymph nodes are not involved, there is a chance of 70% 5 year cure rate.

If the superficial lymph nodes are involved, the cure rate drops to 40%.

If the pelvic lymph nodes are involved the cure rate drops to only 20%.

Friday, May 27, 2011

A Family Doctor's Tale - VESICOVAGINAL FISTULA

DOC I HAVE A VESICOVAGINAL FISTULA

Vesicovaginal Fistula is a chronic granulous track which communicate between the bladder base and the vagina.

Vesicovaginal Fistula usually result from :
1.operation through the vagina causing a hole through vaginal wall to bladder wall

2.follows surgery for hysterectomy

3.Pressure necrosis on the vaginal and bladder walls during a
prolonged and difficult labor.

4.Radiation burns during treatment of cancer of cervix

5.untreated cancer of bladder or genital tract in women

6.Chronic illness such as tuberculosis of bladder or genital tract in women

7.Congenital fistula between bladder and vagina

A veiscovaginal fistula have a natural tendency to close by granulation and fibrosis.

Factors interfering with this are:

1.continual flow of urine

2.sepsis

3.persistance of causative factor such as malignancy or radiation necrosis.

However if the urinary stream can be diverted by a cathether and good bladder drainage and if the sepsis is treated, the natural decrease in size will occur.

Many small fistula of 1 cm diameter or less can be expected to close in 2 to 3 months

Symptoms:
1.incontinence

2.painful urination

3.frequent urination

4.vaginal discharge or wetness

5.painful vagina

Diagnosis:
1.Vaginal examination can show presence of fistula on the roof of vagina

2.Dye instilled into the bladder shows the dye leaking from the roof of vagina

3.Intravenous pyelogram also can show the contrast leaking into the vagina on X-ray.

Treatment of small fistula:
1.The urinary stream can be diverted by a cathether and good bladder drainage

2.The sepsis is treated with antibiotics
Without infection and the constant leakage of urine, the fistula will naturally decrease in size.

Many small fistula of 1 cm diameter or less can be expected to close in 2 to 3 months

3.If this does not happened, the fistula can be easily stitched up.

Treatment of larger fistula:
The vaginal skin is cut open bigger than the fistula for the fresh edges to be stitched.

The granulated hardened edges of the original fistula will not join together so easily as when fresh new tissues are cut and stitched together.

A catheter is left in the bladder to drain the urine and antibiotics are given to prevent infection.

Painkillers may be given if there is pain after the operation.

General treatment:
1.Treatment of associated diseases like diabetes,  carcinoma

2.Antibiotics - a full course of at least 2 weeks of antibiotics is needed

3.toilet and dressing of the wounds, with application of antibiotic creams

4.tub baths of the Vesicovaginal region several times a day in plain, warm water for about 10 minutes

Prognosis is good with surgery.
Rarely there may undesirable complication like urinary incontinence.

Wednesday, May 25, 2011

A Simple Guide to Encephalitis

A Simple Guide to Encephalitis
-----------------------------------

What is Encephalitis?
---------------------------

Encephalitis is a serious medical disease which causes inflammation and infection of the brain.

What are the causes of Encephalitis?
----------------------------------------

The causes of Encephalitis may be divided into:

Infections:
------------
1.viral infections are the most common
(herpes simplex virus, mumps, measles, rubella, chickenpox, West Nile Encephalitis, Japanese Encephalitis, St Lious Encephalitis).

Of these viruses, herpes simplex virus is the most serious and can cause fatality.

2.bacterial infections such as meningoccocus(Neisseria meningitidis) and pneumococcus(Streptococcus pneumoniae) can be serious and fatal in some cases.

Meningococcal Encephalitis can cause outbreaks(spread easily).

3.fungi,
Cryptococcus neoformans is the most common cause of fungal Encephalitis

4.Parasitic
Examples are Toxoplasmosis, malaria, amoeba, Lyme Disease

What are Signs and symptoms of Encephalitis?
---------------------------------------------

The symptoms which often defines Encephalitis are:

1.Severe headache

2.Fever

3.Irritabilty

4.Confusion

5.Drowsiness and fatigue

Other symptoms are:

6.seizures and convulsions

7.vomiting

8.hallucinations

9.memory problems

10.tremors

11.weakness of the hands and legs

12.incontinence of urinary and bowel movement

How is the diagnosis of Encephalitis made?
------------------------------------------

1.Typical symptoms of fever, headache, confusion .

2.Physical examination shows confusion ,drowsiness and signs of neck rigidity

3.blood tests (complete blood count, ESR and blood culture) 

4.cerebrospinal fluid analysis (CSF) via lumbar puncture is examined for increased white blood cells and protein content,  normal glucose level. Red blood cells may be present if there is bleeding. Sometimes the CSF may show the presence of micro-organisms.

This test should not be done if there is suspected cerebral mass lesion or raised intracranial pressure (head injury, localizing neurological signs, or signs of raised ICP).

5.CT or MRI of the brain and spine with MRI preferred over CT because it can detect more easily areas of cerebral edema,tumors, ischemia, and meningeal inflammation.

What are the complications of Encephalitis?
-----------------------------------------------

1.Neurological deficits

2.deafness

3.learning disorders in children

4.brain infarction,

5.septic shock,

6.adult respiratory distress syndrome 

7.seizures also more in children

8.pneumonia especially in the elderly

What is the treatment of Encephalitis?
------------------------------------

1.Hospitalisation should be immediate as Encephalitis is an life threatening condition.

2.Antibiotics such as cephalosporin, ampicillin, chloramphenicol, intravenous vancomycin to be started even before doing lumbar puncture.

Acyclovir may be given for herpes virus infection

High dosages of antifungals may be given for Fungal Encephalitis for a prolonged period of time

3.corticosteroids is useful to reduce swelling and inflammation in the brain

4.Sedatives may be needed for irritabilty and restlessness

5.High-flow oxygen

6.intravenous fluids

What is the prognosis of Encephalitis?
------------------------------------------

This depends on the severity and type of infection.

Viral infections except for herpes simplex usually recover quickly.

Bacterial infections such as meningococcus and pneumonia are more dangerous.

What are the Preventive measures taken for Encephalitis?
--------------------------------------------------------

Vaccinations against Haemophilus influenzae in children and adults has reduced the incidence of this form of meningitis and encephalitis.

Mumps vaccination as part of Measles,mumps and rubella vaccine(MMR) has reduced the incidence of mumps related form of meningitis and encephalitis

A Family Doctor's Tale -UTERINE PROLAPSE

DOC I HAVE UTERINE PROLAPSE

Uterine prolapse occurs when the ligaments and muscles holding the uterus in place has weakened to allow it to drop out of the vagina especially in a squatting position.

Causes of Uterine Prolapse:

1.Pregnancy and childbirth  -the physical trauma of  child birth can strain the pelvic muscles and ligaments to the extent that they are not as strong as before childbirth

2.large fibroids or pelvic tumors can cause pressure on the pelvic muscles downward by gravity

3.age  and menopause can weaken the pelvic muscles and the elasticity of the ligaments

4.Heavy lifting as in manual work can also strain and damage pelvic muscles

5.overweight women are more prone to prolapse

6.Pelvic or spinal surgery may damage nerves and  pelvic muscles increasing the risk of prolapse.

7.Genetic conditions or muscle dystrophy conditions may be responsible for weak muscles


8.Chronic coughing from smoking or the straining due to  constipation, increases the risk of prolapse

Symptoms and signs of uterine prolapse are:

1.Heaviness or protrusion out of the vagina

2.Some thing dropping out of the vaginal area

3.Discomfort or pain in pelvis, abdomen or back

4.Vaginal discharge is excessive or unusual

5.Frequency of urination or urine infection

6.Loss of control of urination(incontinence)

Symptoms may be worse in the evening after prolonged standing or walking

Signs of Uterine prolapse are:

1.Physical examination may show a protrusion of the uterus on squatting.

2.Vaginal examination show the degree of uterine prolapse especially in the standing position:

Stage I   Descent of the uterus to any point in the vagina above the level of the hymen

Stage II Descent to the level of the hymen

Stage III - Descent beyond the hymen

Stage IV - Total prolapse

3.Ultrasound of the pelvis may exclude other conditions than uterine prolapse

Treatment of Uterine Prolapse :

Conservative usually for mild cases of uterine prolapse:

1.Kegel exercises help to strengthen the pelvic floor muscles.

The patient is asked  to tighten the pelvic muscles by tightening the anus for a few seconds and then release many times a day.

2.Vaginal pessary is a rubber or plastic device which is placed around or under the cervix to  support the uterus and hold it in position.

Regular removal and cleaning is important to prevent infection.

It is a temporary measure.

Surgery:

This is the more permanent method of treatment.

1.Colpocleisis involves the removal of a part of anterior and posterior vaginal wall and closing of the margins of the two walls resulting in a small vaginal canal.

The uterus is thus unable to drop out of the smaller vaginal canal.

Success is 90-100%.

2.Sacrospinous fixation is a procedure where the uterosacral ligaments bilaterally is  sutured to the sacrospinous ligaments preventing the prolapse.


3.Sacrohysteropexy make use of a strip of synthetic mesh to hold the uterus in place in an operation done through a 15-cm incision or laparoscopy. One end of the mesh is attached to the cervix and top of the vagina and the other to the sacrum thus supporting the uterus.

4.Vaginal hysterectomy -the uterus is removed through the vagina and the uterosacral and cardinal ligaments are sutured together.


5.Abdominal hysterectomy is done when there is pelvic inflammatory disease or previous intra-abdominal operation when a vaginal hysterectomy is not advisable. The uterus is removed followed by a vaginal anterior and posterior colporrhaphy.


Prognosis of uterine prolapse indicates the treatment in most cases will relieve the symptoms and discomfort.

Prevention of uterine prolapse :

1.Avoid constipation by taking a healthy diet

2.Pelvic muscle exercise (Kegel exercises) should be done regularly

3.Avoid straing of pelvic muscle by using correct lifting techniques

4.Avoid smoking to prevent a chronic cough

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