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Friday, November 4, 2011

VITAMIN B5 DEFICIENCY

DOC I HAVE VITAMIN B5 DEFICIENCY

Vitamin B5(Pantothenic acid) Deficiency is a medical condition caused by the deficiency of the human body of Vitamin B5 as a result of inadequate dietary intake or impaired absorption.

Functions of Vitamin B5:
1.Vitamin B5 plays an important role in the secretion of hormones, such as cortisone because of the role it plays in supporting the adrenal gland.
These hormones assist the metabolism:
2.It is essential for metabolism of fats,carbohydrates and protein 
to make fatty acids and cholesterol.
3.It help to fight allergies
4.It assists in the the maintenance of healthy skin, muscles and nerves.
5.It is used in the creation of lipids, neurotransmitters, steroid hormones and hemoglobin.
6.pantothenic acid is also helpful to fight wrinkles as well as graying of the hair.

Vitamin B5 is found primarily in
1.Beef,  eggs, organ meats. kidney,  liver,  pork,  saltwater fish,
2.fresh vegetables, legumes,mushrooms, nuts, torula yeast, whole rye flour, Whole grains,royal jelly,brewer’s yeast,

Optimal requirements of Vitamin B5 are:
1.adults and children above puberty: 5 mg to 10mg daily
Pregnant mother and elderly may need double the amount.
2.Infants and children before puberty: 5 mg daily

Causes:
Vitamin B5 Deficiency occurs
1.when there is Vitamin B5 deficiencies due to
a.diet - starvation,lactating mothers should take more Vitamin B5
b.malabsorption as in celiac syndrome, sprue or hepatitic cirrhosis
2.Vitamin B5 can be lost in cooking -
a.particularly with roasting or milling,
b.when exposed to acids like vinegar,
c.alkali such as baking soda.
d.It is also destroyed to a large degree in canning.
3.People under stress,
4.prone to allergies,
5.consuming alcohol 
6.eating too many refined foods can develop a shortage of this vitamin.

Severity of Vitamin B5 deficiency is inversely related to age.
It is more common in elderly people.

Symptoms:
1.Vitamin B5 Deficiency is a silent disease in the early stages.
People with Vitamin B5 Deficiency often do not know that they have the condition.

2.fatigue,

3.headaches,

4.nausea,

5.tingling in the hands, numbness, paresthesia (abnormal sensation such as "burning feet" syndrome)

6.depression,

7.personality changes,sleep disturbances

8.cardiac instability .

9.Frequent infection,

10.muscle weakness and cramps

Diagnosis:

1.Blood Vitamin B5 levels are low
2.lowered blood cholesterol,
3.decreased serum potassium, 
4.failure of adrenocorticotropin to induce eosinopenia.
5.increased insulin sensitivity,

Treatment:
The goal of Vitamin B5 Deficiency treatment is the prevention of peripheral neuropathy and skin lesions.

Therefore, prevention of Vitamin B5 Deficiency is as important as treatment. Vitamin B5 Deficiency treatment and prevention measures are:

Medications:
Vitamin B5 supplements
1.Vitamin B5 is given at 10-20 mg per day orally until the response is adequate.

2.It is most effective when taken with the B group vitamins, Vitamin A, vitamin C and Vitamin E.

Side effects are:
1.Vitamin B5 does not give side effects because being water soluble it is excreted easily in the urine if large doses are ingested

2. diarrhea, digestive disturbances and water retention have been reported on dosage exceeding 10 g a day.

Prognosis:
1.good response to treatment in Vitamin B5 deficiency in early stages.

2.treat underlying cause such as malabsorption to get a good response in the treatment of Vitamin B5 Deficiency.

Prevention:
take more red meat, liver, egg yolks, cereals and fresh green vegetables.

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